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A N N A L E S A C A D E M I A E M E D I C A E S T E T I N E N S I S
R O C Z N I K I P O M O R S K I E J A K A D E M I I M E D Y C Z N E J W S Z C Z E C I N I E
2007, 53, 2, 72–82
KRZYSZTOF PRAJS
JAKOŚĆ ŻYCIA CHORYCH NA REUMATOIDALNE ZAPALENIE STAWÓW
W ODNIESIENIU DO SPRAWNOŚCI FIZYCZNEJ I STANU PSYCHICZNEGO*
THE QUALITY OF LIFE OF PATIENTS WHO SUFFER FROM RHEUMATOID
ARTHRITIS IN REFERENCE TO THEIR PHYSICAL FITNESS AND MENTAL STATE*
Klinika Reumatologii Pomorskiej Akademii Medycznej w Szczecinie
ul. Unii Lubelskiej 1, 71-252 Szczecin
Kierownik: dr hab. n. med. Marek Brzosko
Summary
Introduction: A chronic inflammation leads to joints
deformations, which in consequence results in disability
and decrease in quality of life. In the 1960s, the evaluation
of the treatment of patients with chronic disease started to
include quality of life.
The aim of the study: to evaluate quality of life in pa-
tients with rheumatoid arthritis (RA) on the basis of chosen
questionnaires; to determine the usefulness of chosen ques-
tionnaires in assessing quality of life of patients suffering
from rheumatoid arthritis; to investigate whether quality
of life of patients with rheumatoid arthritis depends on
radiological and functional stage of disease, its duration,
their age, sex and activity of the disease.
Material and methods: The study involved RA patients
treated in the Department of Rheumatology and Rheuma-
tologic Outpatient Clinic SPSK-1 in Szczecin. Patients’
quality of life was evaluated with following questionnaires:
Medical Outcomes Study 36-Item Short Form (SF-36), the
Health Assessment Questionnaire (HAQ) and Arthritis
Impact Measurement Scale (AIMS). The quality and un-
derstanding of all scales were tested with Cronbach test
for reliability. The results were statistically analyzed using
Spearman test, the χ
2
test or the χ
2
test with Yates’ cor-
rection, Kruskal–Wallis test and analysis of variance and
covariance. The study group consisted of 155 RA patients
(117 females and 38 males). No significant differences were
found between males and females in age and in degree of
radiological changes.
Results: The value of α-Cronbach’s reliability factor
accounted 0.99, 0.93, 0.81 in AIMS, HAQ and SF-36 ques-
tionnaires respectively. There were significant correlations
between questionnaires and their scales, particularly in
regard to physical fitness. The correlation between HAQ
score and AIMS Physical Functioning scales in total and SF
Physical Functioning accounted 0.78 and 0.67 (p < 0.001)
respectively. No differences in evaluation of quality of life
between men and women were found. No correlation was
found between both the duration of RA and the age of
patients and the activity of the disease as measured with
DAS 28 indicator; correlation coefficient accounted 0.07
(p = 0.39) and 0.11 (p = 0.16) respectively. However, older
subjects with longer duration of a disease and more ac-
tive inflammatory process assessed their quality of life as
poorer (correlation coefficient between DAS 28 and HAQ,
AIMS Physical Functioning scales in total, SF-36 Physi-
cal Functioning accounted = 0.44, 0.43, -0.41 respectively;
p = 0.0000. In addition, the radiological and functional
stage of disease influenced essentially the assessment of
the quality of life in examined group.
Conclusions: 1. The questionnaires used in the study:
HAQ, AIMS and SF-36 were highly useful and they mutu-
ally correlated significantly in assessing quality of life of
patients suffering from rheumatoid arthritis. 2. High mutual
correlation of the questionnaires assessing Quality of Life
* Zwięzła wersja rozprawy doktorskiej przyjętej przez Radę Wydziału Lekarskiego Pomorskiej Akademii Medycznej w Szczecinie. Promotor:
dr hab. n. med. Marek Brzosko. Oryginalny maszynopis obejmuje: 102 strony, 55 tabel, 31 rycin, 128 pozycji piśmiennictwa.
* Concise version of doctoral thesis approved by the council of the Faculty of Medicine, Pomeranian Medical University in Szczecin. Promotor:
Marek Brzosko M.D., D.M.Sc. Habil. Original typescript comprises: 102 pages, 55 tables, 31 figures, 128 references.
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