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QT DISPERSION AT REST AND DURING EXERCISE IN HYPERTENSIVE PATIENTS WITH ANGINA AND NORMAL CORONARY ANGIOGRAMS








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QT DISPERSION AT REST AND DURING EXERCISE IN HYPERTENSIVE PATIENTS WITH ANGINA AND NORMAL CORONARY ANGIOGRAMS
M. Popiel, M. Waśniewski, A. Baszko, K. Błaszyk, S. Grajek, M. Prech, A. Cieśliński,
I Department of Cardiology, Karol Marcinkowski University of Medical Sciences, Poznań, Poland

Increased Qt dispersion (dQT) in hypertensive (HA) patients (pts) may be related to left ventricular hypertrophy (LVH) or myocardial ischaemia. Little is known about dQT adaptation to exercise. We studied dQT in 30 HA pts (age 45.8± 8.9, men/women 22/8) with angina, positive exercise test and normal coronary angiograms who were divided into LVH(+) (n=13) and LVH(-) (n=17) groups based on left ventricular mass index (LVM). The dQT was measured before and at peak - exercise test (Bruce protocol).


 

LVH+

LVH-

p


LVMI (g/m2)

143,55± 17.39

92,28± 14.37

<0.001


workload (METS)

9,05± 3,45

11,53± 11,52

NS


R.P.product (x100)

273± 84,83

258± 258,7

NS


DQT rest (ms)

48.54± 10,68

34,12± 11,21

0.001


DQTc rest (Bazett)

54,35± 7,28

39,92± 14,13

0.004


DQT stress

41,54± 17,72

36,47± 16,56

NS


DQTc stress (Bazett)

54,89± 22,71

51,31± 20,88

NS




We found different patterns of dQT response to stress in both groups: dQT was unchanged in 23% of LVH(+) and 41% LVH(-), dQT­ in 46% and 22% (respectively) pts. There was significant correlation between LVMI, dQT and dQTc at rest (r=0.47 p=0,01 for dQT r=0.44, p<0,02 for dQTc), but not at peak exercise (r=0.16, p<0.42 for dQT and r=0.02, p=0.9 for dQTc).
We conclude that in HA pts with angina and coronary angiograms increased rest dQT relates to LVH. General trend for dQTc increase on exercise is observed. Stress provoked dQt alteration occurs independently of LVH.


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© Copyright by Polskie Towarzystwo Kardiologiczne 1998-2000








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