BN17SPI (2)

BN17SPI (2)



Contents

Preface vii Comribuiors ix

1.    Epidcmiology of cardiac hypertrophy 1 W. B Karmel

2.    Clinical assessment of cardiac hypertrophy 11

J.    E. Liu, R. B. Devereux

3.    Gross morpbology of cardiac hyperrrophy 17 Af. J. Daties

4.    Lcft ventricular hypertrophy: alterations in myocyte number, size, shape and siructure 23

K.    Rakusati

5.    Coronary vasculature in hypertrophy 29

S.    Isoyanui

6.    Extracellular matrix and fibrosis in cardiac hypertrophy 37

K. T. Weber, Y. Sun, A. K. Dhalla, R. V Gutuaka

7.    The geometry of ventricular myocardium: myocyte interconnections and the interstitial tissues 45

Af. S. Peters

8.    Gcnes involved in norma! cardiac development 61

A. A. Dempsey, C. C. Liezv

9.    Triggers for cardiac hypertrophy 71

T.    Yamasaki, /. Komuro, Y. Yazaki

10.    Signals and niessengers for cardiac hypertrophy 77 P H. Sugden, A. Clerk

11.    Myocyte contractilc dysfunction in cardiac hypertrophy 85

S. Harding, P Poole-Wilson

12.    Changes in lcft ventricular function in cardiac hypertrophy 93

J. Mayet, R. A. Poale

13.    Cardiac arrhythmias in hypertrophy 101

R.    Wołk, S. M. Cobbe

14.    Repolarisation abnormalities in ventricular hypertrophy 107

G.Han

15.    Altered conduction in left ventricular hypertrophy 113

C.    H. Fry, P. Carey, A. R. Mundy, D. J. Sheńdan

16.    łonie homeostasis in cardiac hypertrophy 121

S.    R. Hauser, K. Dipla, V. Piacentino, B. A. Bailey

17.    Coronary reserve in hypertrophy 127

B.    Schwartzkopff, B. E. Sirauer

18.    Mcchanisms of reduced coronary reserve in cardiac hypertrophy 135

D.    J. Sheridan, M. P Ktngsłmry

19.    Hypertrophic cardiomyopathy 145

L. Carrier, P Charront M. Komajda, K. Schwartz

20.    Management of hypertrophic cardiomyopathy 153

W.J. McKenna, S. Sharma

21.    Physiological hypertrophy (the athletełs heart) 165

C.    Giusii

22.    Rcgrcssion of hypertrophy 171

S.J.Rials

23.    Regression of left ventricular h^ertrophy and anti-hypertensivc therapy 177

R. E. Schmieder

24.    Lcft ventricular hypertrophy and arabulatory blood pressure 185

G. Mancia, G. Parali

25.    The futurę 201

D.    J. Sheńdan

Index 203


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