Tabela 3

TABLE 3: Effect of RNRA extract on excision and Staphylococcus aureus infected wound

Superoxide dis-

Groups    Mean percentage of wound contraction ± SEM    Period of epitheliali- mutase activity of

Day 3	Day 12	Day 21	zation in days	granuloma tissue(U/ mg protein)
Excision Infected	Excision Infected	Excision Infected	Excision Infected	Excision Infected

Control	12.61 ±	15.38 ±	44.00 ±	23.62 ±	73.80 ±	67.29 ±	27.00 ±	35.82 ±	0.87 ±	0.85 ±
	2.31	3.7	2.58	1.6	2.51	1.4	0.03	0.95	0.24	0.76
Betadine	23.96 ±	19.01 ±	100.0 ±	81.20 ±	100.0 ±	100.00 ±	12.62 ±	15.01 ±	1.28 ±	1.29 ±
(5% w/w)	2.3	2.38	1.0***	1.32***	0.0***	0.0***	0.06***	0.02***	0.24*	0.54*
Neomycin	-	20.47 ±	-	100.00 ±	-	100.00 ±	-	12.06 ±	-	1.31 ±
(5% w/w)		2.77		0.02***		0.0***		0.11***		0.35
Ointment base	14.46 ±	19.87 ±	56.32 ±	38.46 ±	82.5 ±	75.45 ±	23.39 ± 0.	29.14 ±	0.85 ±	0.89 ±
	1.94	2.9	1.25***	2 'j ***	1.70***	2.4***	82***	0.84***	0.15	0.54
RNRA 1%	18.44 ±	18.31 ±	70.15 ±	71.40 ±	100.0 ±	100.00 ±	17.04 ±	17.03 ±	1.18 ±	1.11 ±
	1.9	1.92*	1.5***	1.64***	0.0***	0.0***	0.19***	0.92***	0.65	0.42
RNRA 2%	18.68 ±	19.20 ±	91.2 ±	80.63 ±	100.0±0.0***	100.00 ±	13.09 ±	15.13 ±	1.31 ±	1.19 ±
	2.8	1.14*	1.0***	1.06***		0.0***	0.12***	0.43***	0.62*	0.42*

RNRA1, RNRA 2 = Rubus niveus root acetone extract of 1% and 2% w/w ointment. Values are expressed as mean (n = 8) ± SEM.

Significantly different at ***p < 0.001, **p < 0.01, *p < 0.05 when compared to control.