Table 37.7 -- Opportunistic infection prophylaxis and treatment in adolescents and adultslal
Risk factor |
Agent |
Prophylactic medication |
CD4 celi count < 200 cells/pl |
Pneumocystis jiroveci |
rrimethoprim-sulfamethoxazole ;tmp-SMX) or dapsone plus or minus pyrimethamine and eucovorin or aerosolized aentamidine or atovaquone |
Coccidioidomycosis |
In endemic areas: fluconazole or traconazole | |
CD4 T-cell count < 100 colls/nl |
Toxoplasma gondii |
TMP-$MX or dapsone plus pyrimethamine plus leucovorin or atovaquone plus pyrimethamine plusleucovorin |
Histoplasmosis |
In endemic areas: itraconazole | |
CD4 T celi count < 50 cells/nl |
Mycobocterium ovium complex {MAC) |
Macrolide (clarithromycin or azithromycin) or rifabutin |
Cryptococcosis |
In endemic areas: fluconazole or traconazole |
Rich ct ol. ćlimcol Immunology 2008