IMG 84 (4)

Polymeric and secretory immunoglobulin A

B. PolylgA cousists of twomlgAmolecules linked end to eiid with J chain banding to both mlgA subunits via cysteinę (Cys) 471 of one a-chain fromeach monomer

1. Secretory component (SC) binds only to polymeric IgA or IgM

2. SC binding by plgA and IgM is dependent on the prcsence of J

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