DSC03054

Figurę MS. tmniune coniplexe$ bound to foilicuiar dendritie cetls form iccosomes, which ar* reieased and can be tak en up by B celłs in the germinal center. Folficuiar dendntic eełls have a prominent Ml body and many dendritie processes. Immune complexes. bound to eomplement and Fc receptors on the foilicuiar dendritie celi surface. become clustered. forming prominent 'beads' along the dendrtes An inlerrnediate form of foicular dendritie celi a stawu (left panel) wih both straight tttform demttes and those that are becoming beaded. These beads are stad from the celi as iccosomes t immune compfoicoated bodies). which can bind (center panel > and be taken up by B cefc m the germtnai center (right panei i. In the cent* and right panels. the iccosome has been formed wth immune complexes contammg hnrunuiih iwcuidase. which is etectrondense and thus appears dark in the transmesjon eieetron morogrtpht. Pńotographscourtesy of A.K. Szakal,    1989; ?:9M09l