Shear
stress
Estrogen Insulin Statins
Leptin
(iii)
Unphosphorylated
Endothelial dysfunction
•i- Blood flow Thrombosis Inflammation Neointima formation
T Vascular reactivity
T Blood flow 4- plt aggregation -i- LE-interactions 4- sm mm proliferation
DEPARTMENT OF MEDICAL BIOTECHNOLOGY Faculcy of Biochemistry, Biophysics and Biocechnology
Huang PL. Trands Endorcrin Matabol 2009.