60S
elF6
g^elF4F
Ribosomes
PABP1
AAAA
O
Translation
Dcp1
Compete for cap binding
AUG
Compete for elF6/60S
miRISC
Promote degradation
I
UIIIIIIUIIII
CCR4
CAF1
NOT
Ribosome dropoff
Błock circularization