8851686613

8851686613



• Lecture:

Particular lectures contents

Number of hours

1 Introduction. Chemical bonds In biochemistry. Entropy and the laws of thermodynamics. Protein structure and function: amino acids and primary structure

3

2. Protein structure and function - cont. - secondary, tertiary and quaternary structure, Anfinsen experiment, protein folding

2

3.Exploring proteins - the purification of proteins: gel filtration, affinity chromatography, ion-exchange chromatography, ultracentrifugation, activity tests, gel electophoresis, evaluation of purification scheme: quantification of a purification protocol (yield, level), amino acid sequencing - Edman degradation, mass spectrometry

3

4. Exploring proteins - cont. - immunology provides important techniques with which to investigate proteins, automatic solid-phase peptide synthesis, three-dimensional protein structure: NMR spectroscopy and X-ray crystallography, proteom description

3

5.Hemoglobin - portrait of allosteric protein - allosteric regulators with 2,3-BPG, hydrogen ions and C02, hemoglobin transports oxygen efficiently by binding oxygen cooperatively, the Bohr effect, sicie anemia

2

6.Enzymes - basie concepts and kinetics - cofactors for activity, and the reaction spontaneity, the active sites of enzymes, the formation of the transition State ES, the Michaelis-Menten model, the significance of Kand Vmav, the kca,/Km criterion, enzyme specific inhibitors, competitive and noncompetitive inhibition, catalytic antibodies, penicillin, vitamines

3

7.Catalytic strategies - proteases: facilitating a difficult reaction, carbonic anhydrases, restriction enzymes, nucleoside kinases

2

8.Regulatory strategies - aspartate transcarbamoylase, isoenzymes covalent modification, specific proteolytic cleavage, blood clotting

2

9. Carbohydrates - complex carbohydrates conformation, glycoproteins, lectins

1

10.Lipids and celi membranes - common features, constituents of lipids, bilayer permeability, the fluid model mosaic model, compartments in eucaryotic cells

3

11.Membranę channels and pumps - the transport of molecules across a membranę may be active or passive, ATPases protein family, multidrug resistance, secondary transporters, patch-clamp conductance measurements, specific voltage-gated channels, gap junctions

3

12.Metabolism - basie concepts and design - coupled reactions, regulatory strategies, evolution of metabolic pathways

3

• Classes - the contents:

19



Wyszukiwarka

Podobne podstrony:
Particular lectures contents Number of hours 1.    Kinematics: two and three dimensi
• Lecture: Particular lectures contents Number of hours 11. Fundamentals of
• Lecture: Particular lectures contents Number of hours 11. Fundamentals of
Lecture Particular lectures contents Number of hours 1. Economic activities act 2 2. Civil
Lecture Particular lectures contents Number of hours 1. Elementary terms (linear and branched
PROGRAMME CONTENT Form of classes - lecture Number of hours
PROGRAMME CONTENT Form of classes - lecture Number of hours
PROGRAMME CONTENT Form of classes - lecture Number of hours Lec 1 Number systems and codes, fixed-
PROGRAMME CONTENT Form of classes - lecture Number of hours
PROGRAMME CONTENT Form of classes - lecture Number of hours Lec 1,2 Organizational matters. Signal
PROGRAMME CONTENT Form of classes - lecture Number of hours Lec 1,2 Organizational matters. Signal
PROGRAMME CONTENT Form of classes - lecture Number of hours Lec 1 Manufacturing technologies and l
PROGRAMME CONTENT Form of classes - lecture Number of hours Lec 1,2 Organizational matters. Signal
PROGRAMME CONTENT Form of classes - lecture Number of hours Lec 1,2 Organizational matters. Signal
• Lecture: Particular lectures contents Number ofhours 1. Biocatalysis as an element of Green
• Lecture: Particular lectures contents Number ofhours 1. Content of the lecture. Basic informati
• Lecture: Particular lectures contents Number ofhours 1. Introduction. Signal and noise
Form of classes - lecture Number of hours Lec 1,2 Organizational matters. Signals in time and freąu

więcej podobnych podstron