KATALIZA KATALIZA ASYMETRYCZNA ORGANOKATALIZA UMCS - Studia Doktoranckie XI - XII. 2008 KATALIZA ASYMETRYCZNA z udziaÅ‚em metali przejÅ›ciowych The Nobel Prize in Chemistry 2001 "for their work on chirally catalysed hydrogenation reactions "for his work on chirally catalysed oxidationreactions" William S. Knowles Ryoji Noyori K. Barry Sharpless 1/4 of the prize 1/4 of the prize 1/2 of the prize USA Japan USA Nagoya University The Scripps Research Institute St. Louis, MO, USA Nagoya, Japan La Jolla, CA, USA b. 1917 b. 1938 b. 1941 Dr William S. Knowles Prof. Ryoji Noyori Prof. K. Barry Sharpless PPh3 PPh3 Pdo Ph3P PPh3 Rh Cl Ph3P PPh3 PPh3 Malatesta Wilkinson William S. Knowles William S. Knowles William S. Knowles William S. Knowles William S. Knowles William S. Knowles William S. Knowles William S. Knowles William S. Knowles William S. Knowles William S. Knowles William S. Knowles Qudrant rules William S. Knowles William S. Knowles Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori Ryoji Noyori K. Barry Sharpless Asymmetric epoxidation of allylic alcohols K. Barry Sharpless Asymmetric epoxidation of allylic alcohols K. Barry Sharpless Asymmetric epoxidation of allylic alcohols Chirally predictive model K. Barry Sharpless Asymmetric dihydroxylation of olefins AD-mix ² AD-mix Ä… K. Barry Sharpless K. Barry Sharpless Asymmetric dihydroxylation of squalene K. Barry Sharpless K. Barry Sharpless K. Barry Sharpless