16. UZYWANE SKROTY

Kursywy uzywa sie dla oznaczenia genow, zarowno w pelnej formie jak i w skrocie, oraz dla oznaczenia lacinskich nazw jednostek taksonomicznych. W przypadku drozdzy, geny szczepu dzikiego pisze sie duzymi literami a geny zmutowane malymi literami. W skrotach genow zlozonych z liter i cyfr w zasadzie nie robi sie odstepu miedzy literami a cyframi. Homologiczne geny w roznych gatunkach niekiedy oznacza sie przez dodanie litery np. h (human); y, (yeast); m, (mouse); d, (drosofila)

Nomenklatura genow

Homo:

http://www.gene.ucl.ac.uk/nomenclature/guidelines.html

http://www.gdb.org

E. coli:

http://genolist.pasteur.fr/Colibri/

S. cerevisiae :

http://genome-www.stanford.edu/Saccharomyces/

D. melanogaster:

http://flybase.bio.indiana.edu/

E. coli	S. cerevisiae	Mus musculus
mutS ( skrot od slowa mutator)	MSH2 (skrot od mutS homologue), yMSH2	Msh2, mMsh2	gen szczepu dzikiego
mutS Ż	msh2	msh2, Msh2Ż	gen zmutowany
MutS	Msh2	mMSH2	bialko

A

abd-A abdominal-A

Abd-B Abdominal-B

ada adaptive response (gen kodujacy DNA-metylotransferaze

O⁶-metyloguaniny)

ADHD attention deficit/hyperactivity disorder

Alu sekwencja powtarzajaca sie w genomie naczelnych

Antp Antennapedia

A/P anterior/posterior (os przod-tyl zwierzecia)

AP AP nukleaza (apurynowo/apirymidynowa, glikozylaza liaza)

AS-C Achaete-Scute Complex (genow drosofili)

ATM ataxia telangiectasia mutated

ATR ataxia telangiectasia rad3 related

ATRIP ATR-interacting protein

B

bcd bicoid

BER base excission repair

BMAL brain-muscle-arnt-like-protein (Arnt - aryl hydrocarbon receptor nuclear translocator)

BRCA brest cancer

BRCT BRCA carboxy terminal

Brm brahma

BRG-1 brahma related gene

C

CAF1 Chromatin Assembly Factor

cad caudal

CARM1 co-activator associated arginine methyltransferase

Cbf1 centromere binding factor (bialko)

CBF3 centromere binding factor (kompleks bialkowy)

CBP/P300 CREB-binding protein

cc central core (element centromeru S. pombe)

Cdc cell division control

CDEI, II, III conserved DNA element I, II, III

CEN sekwencja centromerowa w S.cerevisiae

CENPA,B... centromeric protein A, B....

cep C. elegans P-53-like protein

CID centromere identifier

Cot iloczyn Co (stezenie) i t (czasu)

CP1 chromatin protein

CREB c-AMP responsive element binding protein

CRY cryptochrome

CSA,CSB Cocayne syndrom grupa komplementacji A,B

Cse4p chromosome segregation

CTD carboxy terminal domain

CTCF CCCCTC binding factor

CYC cycle

D

dbt doubletime

dClk drosophila clock

dfd deformed

DinB damage inducible

Dl delta

Dll distalless

DM double minute

Dnmt1 DNA methyltransferase

dpp decapentaplegic

DR direct repeat

DRD4 dopamine receptor

DSPS delayed sleep phase syndrom

D/V dorsal/ventral

E

EN endonuclease

en engrailed

env envelope

ERCC1 excission repair cross complementing gene 1

ES embryonic stem (komorki)

EST ever shorter telomeres

ey eyeless

eve even skipped

F

FACT facilitates chromatin transcription

FAD, FADH nukleotyd flawiniwo adeninowy forma utleniona

zredukowana

FASPS familial advanced sleep phase syndrom

FEN1 5' - 3' flap exo/endonuclease

FLA free left Alu

for foraging

Fpg formamidopyrimidyne glycosylase

FRA free right Alu

G

G (prazki) Giemza

gag group specific antigene

GR, Grl glucocortycoide receptor

H

HAT histone acetyltransferase

hb hunchback

hBRM human brahma

HDAC histone deacetylase

8HDF 8-hydroksy-5-deazaryboflawina

HERV human endogeneous retrovirus

hh hedgehog

H3-K27 lizyna w pozycji 27 histonu H3

HMG high mobility group

HML homothallic mating left

HMR homothallic mating right

HMT histone methyltransferase

HO homothallic (nuclease)

Hox homeobox

HP1 heterochromatin protein 1

HS hypersensitive sites

HSR homogeneously staining region

HSV herpes simplex virus

I

IR inverted repeat

ISWI imitation switch

L

L1 long (repetitive sequence element)

LCR locus control region

LEU2 leucine (gen kodujacy dehydrogenaze -3-

izopropylomaleinianu)

lexA lambda excission

LINE Long interspersed repetitive element

LTR long terminal repeat

loxP gorace miajsce ekombinacji faga P

LUCA last universal common ancestor

M

MAR matrix attachment region

MATa,  mating type

MBD2 methylCpG binding domain

MCAK mitosis-specific centromere associated kinase

MeCP2 methyl-CpG binding protein

MMR mismatch repair

MMTV mouse mammary tumor virus

MNNG N-metylo-N'nitro-N-nitrozoguanidyna

MRE meiotic recombination

M/R/N MRE11-RAD50-NBS1, meiotic recombination

radiation sensitivity/Nijmgen breackage syndrom

MRP multidrug resistance protein

MSY1 minisatellite on the chromosome Y

MTH MutT homologue

MTHF metenylotetrahydrofolian

MutT, Y mutator

MVR-PCR minisatellite variant repeat polymerase chain reaction

MYH MutY homologue

N

N notch

NAP1 Nucleosome assembly proteine

NBS Nijmgeen breakage syndrom

neo^r neomysine resistant

NER Nucleotide excission repair

NES nuclear export sygnal

NF1 nuclear factor

NHEJ non-homologous end joining

NLS nuclear localisation sygnal

NMDA N-methyl-D-asparate

nos nanos

npr-1 neuropeptide receptor

NR neighbor relation (metoda)

NR1,2 NMDA receptor 1,2

NTG endonuclease of thymine glycol

NuRD nucleosome remodeling and histone deacetylase

O

OGG1,2 8-oxo-guanine DNA glycosylase

ORF open reading frame

OJT operacyjna jednostka taksonomiczna

P

Pb proboscipedia

PACAP pituary adenylate cyclase activating peptide

PcG polycomb group

PCR polymerase chain reaction

PCNA proliferating cell nuclear antigen

P/D proximo/distal

per period

PGK protein cGMP dependent kinase

pN piko Newton (jednostka sily)

pol polymerase 

 , ,  polymerase I, II ..

Q

Q (prazki) Quinacrine

R

r rover (ang. wloczega)

R (prazki) reciproques

7R allel DRHD posiadajacy 7 VNTR

RAD radiation abnormal sensitivity

RAM random access memory

Rap represor-activator protein

RB retinoblastoma (gen supresora nowotworow)

REB1 rDNA enhancer binding protein

RecA recombination

RFLP restriction fragment length polymorphism

RNAPI, II.. RNA polymarase

RPA replication protein A

RSC remodel structure of the chromatin

RT reverse transcriptase

RTH Retino-hypothalamic tract

RXR retinoid X receptor

S

s sitter

SAR scaffold-associated region

SCC sister chromatid cohesion

SCN suprachiasmatic nuclei

Scr sex combs reduced

sd scalloped

SELEX systematic evolution of ligands by exponential enrichment

CHK checkpoint

Sin SWI independent

SINE short interspersed element

Sir silent information regulator

SMC structural maintenance of the chromosome

snRNA small nuclear RNA

sog short gastrulation

SOS save our souls

SpCENPA S. pombe centromeric protein A

spi spitz

SRY sex determining region on the chromosome Y

ssDNA single stranded DNA

STAR subtelomeric antisilencing region

STIR subtelomeric interspersed repeats

sunY split gene unknown function why?

Su(hw) supressor of hairy wings

SWI/SNF switch/sucrose non fermenting

sna snail

T

TAD transcription activiation domain

TAF TBP-associated factor

TBP TATA-box binding protein

TBF1, 2.... TTAGGG repeat binding factor

td thymidine synthase

TFIIA, B, ... transcription factor

tim timeless

tk thymidine kinase

TLS translesion synthesis

TRCF transcription-repair coupling factor

TRF1, 2.... telomeric repeat-binding factor

TTDA trychtiodystrophy A

twi twist

U

Ubx ultrabithorax

UmuDC UV mutator

UPGMA unweighted pair group method with arythmetic mean

URA3 (gen kodujacy dekarboksylaze orotydyno-5'fosforanu)

UTR untranslated repeat

UvrA, B, ... ultraviolet resistant

V

vg vestigial

VNTR variable number tandem repeats

VP16 viral protein

W, X, Y, Z

wg wingless

XPA, B, ... xeroderma pigmentosum (grupy komplementacji)

YAP Y Alu polimorfizm

z zerknült

Uzywane skroty

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