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Molccular Evolution- 2013 Exam. vcrslo« B Jarosław Marszalek

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1. Frora the functional perspective mutations in protein coding secjuencc could be divided into 3 classes.

(occurring ofJ^a/p«weły cross out the wrong answer) (occurring aftea/ra^ely cross out the wrong answer) (occurring oł-ton/raptfy craw owf the wrong answer)

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2. (fi/l up the Jol łowing text) In bacterial genomes sequences encoding proteins and RN A consist approximately (A:    /    %) of the total DN Asequence, while in the human genome

protein/RNA coding sequences consist (B: wJS %) of the total DNA sequence.

Genome of Escherichia coli harbors approximately (C: y )protein coding genes, while \^) human genome encodes approximately (D:    3 OOO genes).

The GC/AT content of the genomes is (E) eonstant/yariable ( cross out the wrong answer ) in both prokaryotic and eukaryotic genomes. Genes encoding proteins are (F) highly variable and it is difficult to finds homologs on bacterial genes in human genome/ are highly-oonscrvcd -and ii is roiatively casy to-find-homologs of bacterial^genes in human genomes (cross out the wrong answer). The gene order on chromosomes is (G)-Mghly-variabic in cvoiution/ is highly conserved in evolution (cross out the wrong answer) 3. In 2-3 short sentences explain how NATURAL SELECTION works.

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