100737

Acetaminophen - poisoning

Drug Name

Metoclopramide — Functions as antiemetic by blocking dopamine receptors in the chemoreceptor trigger zonę of CNS. Is generally DOC due to lower cost than ondansetron (Zofran). Adult Dosel0-20 mg IV, not to exceed 1 mg/kg; not to exceed 3 mg/kg/d divided prn Drug Name

Ondansetron (Zofran) — Selective 5-HT3-receptor antagonist that blocks serotonin both peripherally and centrally. Considered potentially morę effective than metoclopramide; in addition, adverse effects are less common. Adult Dosel mg, or 0.15 mg/kg or 8 mg IV q8h, not to exceed 3 doses