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Acetaminophen - poisoning
o Pathophysiology: The maximum daily dose of APAP is 4 g in adults and 90 mg/kg in children. The toxic dose of APAP after a single acute ingestion is 150 mg/kg or approximately 7 g in adults. The at-risk dose may be lower in some susceptible patient populations, such as persons with alcohol abuse. When dosing recommendations are followed, the risk of hepatotoxicity is extremely smali.
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