Acromegaly is an insidious, debilitating disorder resulting in high circulating levels of GH and IGF-I, associated with bony and soft tissue overgrowth. survival reduced - approximately 10 years (mortality increased 2 - 4 x).
» rare disease
» prevalence 60 cases / million » incidence 3.3 new cases / million / year » average age 40 - 50 years » female = małe » diagnosis delay - about 8 lat » Pituitary adenoma - 98% cases