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Strona 2 z 3

Catalytie mechanism of aspaitic proteinases

sii&strsts

Wr

urn ww ui

Hydrogen bond

'Cv

.h /    %\

—OHuiuuutu _sv>% ⁰'uv\ u mu ^H0—

/^CH2 §

Asp —

/ s^x'    ^

' O    * j,

*h. // \

0^ CH₂

tl

\

Asp

X- '1

,CK.= s

KC“

H

\

—oh u umil ni o^-

A

Asp ~

Odiumitni ho—

\

D^/ CH₂

=    \

Z    Asp

^r.

XH™"R ...

HO"

OH

ł

■OH U Ul 1| UU^O"

£\

Asp ~

H

O^WiUUIllHO — /^C\

HO ^Clj2 r    Asp

%

O—OH +

n '

n

„CB—R, ,

✓

-OH ttUUUt lu <?

q" u U\ u U tu HO-