Suppressor gene
RB1 (13ql4) p53 (17pl3)
APC (5q21) WT-1 (11 p 13) NF-l (17qll> NF-2 (22ql2) VHL (3p25) pló(9p21) URCA1 (17q21) BRCA2 (13ql2)
11
Cancer
syndrome
Retinoblastoma
Li-Fraumeni
Familial adenomatous polyposis Wilms' tumour Neurofibromatosis type I Neurofibromatosis type Y1 Von Hippel-Lindau Familial melanoma Familial breasteancer