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CONTENTS

Introduction to the symposium

W.Fimhaber    1Q

14

28

41

51

62

67

70

72

73 79 87

96

104

EditorisJ: Multipie sclerosis in the Oid World: The new old ruap KLauer

Serendipidy and multipie sclerosis epidemiology G.Dean

Multipie sclerosis in Iceland 1 January 1900 - 31 December

1989: A 90 ycars total population study

J.E.G.Benedikz, H. Magnus son, C.M.Poser, G. Gudmundsson

Multipie sclerosis in the Faroes J.F.Kurtzke, ICHyllested, A.Heltberg

The epidemiology of multipie sclerosis in Norway: A 50 year follow up in a sfcable population

M. Grónning

Incidence of multipie sclerosis - A population-based, longitudinal study in M5r< and Romsdal, Norway RMidgard, T.Riise, H.Nyland

Prevalence and incidence of multipie sclerosis in Gothenburg, Sweden, with a discussion on the possible influence of measles and rubella vaccination O. Andersen

Multipie sclerosis and exposurc to solvents, ionizing radiation and animals:

A case-referent study

AM.Landtblom, U.Flodin, M.Karlsson, S.Palhagen,

B.Sóderfełdt, O.Aocelson

Multipie sclerosis in Finland: Evidence of uneven geographic distribution,

increasing frequency and high familial occurrence

J. Wikstróm, P.J.Tienari, M.L.Sumełahti, E.Hovi, E.Kinnunen, J.Palo

The Danish multipie sclerosis registry: A 44-year review

N.Koch-Henriksen, H.Brónnum-Hansen, ICHyllested

Genetic and epidemiological aspects of multipie sclerosis in the United Kingdoi N.P.Robertson, C.J.Mum/ord, D.A.S.Compston

An epidemiological joumey of multipie sclerosis with iinmigrants to the United Kingdom through genes and environment M. Elian

The prevalence of multipie sclerosis in the health district of Bassetlaw KWAllen

hu trusing prevalence and incidence of multipie sclerosis: an epidemiological study in the provincc of Groningen, The Netherlands ,/ M Minderftoud, C. P. Zwanniken

0.1. WSTĘP    7

The natural hisłory of MS in Belgium: A MS clinic-based study

RŁGonsette, F.Lissoir,    P.Theys,    P.Ketelaer.    C.Droissart,    L.Demonty    122

The epidemiology of multipie sclerosis in Southern Lower Saxony

S.Poser    130

Epidemiological analyses on multipie sclerosis in the region of Rostock,

North-East Germany

H. Meyer-Rienecker    134

Epidemiological data on multipie sclerosis from an industrial area in North-West Germany

M.Haupts, P.Schejbal, D.Póhlau,J. Malin,    H. Pmmtek,    W.Gehlen    143

Descriptive and analytical epidemiological data on multipie sclerosis from a long-term study in Southern Hesse, Germany

KLauer, W.Fimhaber    147

Relation in space and time between the frequency of multipie sclerosis and geophysicai factors

J.Resch    159

Epidemiology of multipie sclerosis in Switzerland

J.Kesselring, S.Beer    166

MS as underlying vs. additional cause of deathr Comparisons from Swiss raortality data 1969-1990

M.Schmid, Y.Ajdacic-Gross, A.Tschopp, F.Gutzwiller    168

Multipie sclerosis in the Pyrćnćes-Atlantiques: A case-control study conducted in the Southwest of France

M. P.Roth, S.Ballivet, P.Descoins, J.B.Ruidavets, M.Clanet, A.Cambon-Thomsen    177

Prevalence and incidence of multipie sclerosis in Gijón (Northern Spain)

D. F. Urla, P.Abad, P. Yirgala, M. T. Calatayud    179

Prcvalcnce of multipie sclerosis in Spain: Validation of an epidemiological protocol in two geographically scparated areas

O.Femóndez, E.Bufill    184

Incidence rates of multipie sclerosis in Ąlcoi, Spain

J.Matias-Guiu, L.Galiano, C.Ribera, A.Óltra, R.Martin    190

A matched case-control study on multipie sclerosis in Alcoi

J.Matias-Guiu, LGaliano, LFerri, A.Oltra. R.Martin    191

Epidemiology of multipie sclerosis in Portugal

J.deSd, A. Magalhaes    192

Experieace in multipie sclerosis epidemiology in Italy

E. Granieri, M.R.Tola    I95

The mortality rates for multipie sclerosis in Italy (1969-1987)

N. Yanacore, Y.Bonifati, E.Fabrizio, G.Meco    208