clinical immuno final1 04

25. Uendritic cells:

(&} originate form bonę marrow

B)    are absent in peripheral blood

C)    posses strong endocytosis abilities

D)    present antigens bounded only with MHC class II ^! E) present antigens less effective than macrophages

26. NK cells are defined as:

CD3-CD16+/CD56+

B)    CD3+CD56+

C)    CD3+CD8+

D)    CD3-CD21+

E)    CD3+CD34+

F)    CD3+CD16+

27. Fuli symptomatic AIDS is diagnosed when number of CD4+ cells decrease bellow:

A) 1200/mm³ z-*    B) 1000/mtn³

Ar”    C) 800/mm³

^    D) 400/mm³

<|])200/mm³

28.

ark a true sentence about Fas(CD95) antigen:

Fas analogous is a TNF receptor

B)    Fas expression on B cells decrease after stimulation

C)    cytotoxic celi Fas interaction with its ligand on target celi leads to target celi death

D)    eye and testis cells bear FasL on their surfaces and because of that grafts of these organs are fast rejected

E)    mutations in Fas gene are unknown in humans

29. hi which of disease written bellow temporary autoimmunisation with production of autoantibodies is present:

Myocardial infarction |\ B) Streptococal angina i- -'* C) Chlamydia infection

D)    Lupus postmedicamentosa

E)    Salmonellosis

30. Which of written below factors can polyclona! activate B cells:

/AyEpstein-Bar virus

B) BCG

\

Jj> C) cyclosporine ! D) cow milk protein

E) grass pollen allergens

31.    Mark true pairs: autoimmune disease- its infectious factor:

A)    Type I diabetes- EBV (^JlRheumatic fever- Streptococcus pyogenes

C)    Myasthenia gravis- influence virus

D)    Multiple sclerosis- HIV

E)    Pernicious anaemia- Mycobaeterium tuberculosis

32.    Autoantibodies in autoimmune diseases:

transfer placeta and have an influence on fetus

B)    their pathogenesis is species specific

j\ C) are produced only in disease effected organs H' D) have mistakes in their have chain structures

E) have no abilities to activate the complement system

33.    In Goodpasture’a syndrome autoantibodies against collagen type IV damage basement membranę of:

A) liver sinuses lung vessels

C)    brain vessels

■'©■) jejunum epithelium E) bladder epithelium