6 (887)
Antidiarrheals
Diarrhoea
Diarrhoea involves either an increase in fluid secretion into the gut, a reduction of fluid absorption from the gut or an increase in motility
GUT
jfluid secretion | flŁid absOTPtion 1
Antidiarrheals
• Two types of movement: - Peristaltic
• moves food forward
Tirr»«!3 Ccntrwfiw Bt>^ ?toivis>5$«§iaeftt
StóKKiit &14T BoiliS ;W fcrwaiO
- Segmental • Mixing
• Controlled by parasympathetics
Difm.tio-'; o! sno-.om-jr:!
• Deficiency of lactase at brush border
• Increased lactose provides carbon for bacteria
• Presents as bloating, crampy pain, osmotic diarrhea
Enzymes
|
Effect of Parasympathetic Activity on Gut Smooth Muscle | ||
|
• Certain cells generate slow wave pacemaker potentials |
> mV |
< |
|
• This is increased by ACh |
Force | |
|
TIME | ||
b
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