4602201759

Figurę 3. All-Cause Mortality From Randomization (Day 0) to Day 28 Among Patients With Sepsis-Associated Acute Respiratory Distress Syndrome

601

Treatment period

Gehan-Breslow-Wilcoxon test, P = .01 HR, 0.55 (95% Cl, 0.33-0.90)

Placebo j—

Vitamin C

No. at risk Placebo

0	7	14	21	28
		Days Since Randomization
83	59	53	47	45
84	74	65	61	59

Vitamin C-infused patients exhibited a significant reduction in 28-day all-cause mortality. although the P value was not adjusted for multiple comparisons.

The median observation time was 28 days (interquartile rangę, 15-28 days) for the vitamin C group and 28 days (interquartile rangę, 5-28 days) for the placebo group.