147098299

"^Hydride Reduction Reactions

OH

A

OH

A

Reduction of an Aldehyde to a 1’Alcohol

V    1. NaBKł. EtOH^

2. H₃0*

9    1.LiAIH_4l EtOH ^

2. H₃0⁺

2. H₃O^ł

OH

A

Reduction of a Ketone to a 2’Alcohol

°    1. NaBH_4l EtOH

O

A

1 LiAIH₄, EtOH 2. H₃0*

OH

-A

Reduction of a Carboxyłic Acid to a 1‘Ałcohol

O

A

1. LiAlH₄. EtOH

OH

OH 2. H₃0"

-A

Reduction of an Ester to a 1 ‘Alcohoł

OH

O 1. LiAIH₄, EtOH ^    .

2. H₃0*

+ —OH

Reduction of an Ester to an Aldehyde

1 DIBAL-H. -78°C __    °

Reduction of an Acył Chloride to a 1'Alcohol

OH

°    1. LiAlH₄, EtOH ^    ,

^Cl 2. H₃0⁺    *"^H

Reduction of an Acyl Chloride to an Aldehyde

Reduction of an Amidę to an Aminę

Hoffmann Rearrangement

n LiAIH[OC(CH₃)3b _    °

0

1. LiA)H₄. EtOH

NH₂ 2. H₃0*

'nh₂

O

AC

1. Br,

^NH2 2. NaOH

NH,

nh₂

Reduction of a Nitrile to an Aminę

__n 1.UAIH₄, EtOH 2. H₃0⁺

Aud a«oiyze^ <? jp

cte    ₀-

(A

A t    Coi

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