5441336579

UP MS General Medianę major - suhjerts (filie Pre-clinical module - Course descriptions -,wadem lic yearof2015/2016

11	Histaminę and antihistaininic drugs Dr. Barthó Lorand
12	Pharmacology of eicosanoids Dr. Pethó Gabor
13	Pharmacological significance of tire sensory' neuron mediators Santicsne Dr. Pintćr Erika
14	Pharmacological aspects of the purinergic system and nit Santicsne Dr. Pintćr Erika	neonie
Practices
Seminars
1	Introduction to pharmacology
2	Drug names. drug compendia. prescription writing
3	Basic mechanisms of drug actions
4	Characterization of agonist-receptor interaction I
5	Characterization of agonist-receptor interaction II
6	Characterization of agonist-receptor interaction III
7	Signal transduction mechanisms of dnig receptors
8	Tachyphylaxis and tolerance to drugs
9	Mechanisms of drug antagonisms I
10	Mechanisms of dnig antagonisms II
11	Transport of dmgs across membranes
12	Absorption of dmgs
13	Distribution of dmgs I
14	Distribution of dmgs II
15	Biotransfonnation of dmgs I
16	Biotransfonnation of dmgs II
17	Biotransfonnation of dmgs III
18	Excretion of dmgs
19	Quantitative aspects of pharmacokinetics I
20	Quantitative aspects of phannacokinetics II
21	Dmg development I
22	Dmg development II
23	Dmg formulations I
24	Dmg fonnulations II
25	Dmgs acting on smooth muscle I
26	Dmgs acting on smooth muscle 11
27	Dmgs acting on the respiratory traci I
28	Dmgs acting on the respiratory' tract II
Exam topics/questions

1. Definition of pharmacology and tlie relaied subjecls. Drug developmenl

2. Dnig names. drug compendia. Prescription wriling

3. Drug fonnulations

4. Basic mechanisms of drug actions (examples of drug effects on receptois. ion channels, enzymes, carrier Systems and effects mediated

by physicochemical interactions)

5. Characterisation of agonist-receplor interaction: occupancy. affinity, dose-response curve, potency, efficacy

6. Significance of signal transduction mechanisms in the effects of dmgs. Tachyphylaxis and tolerance to dmgs

7. Mechanisms of drug antagonisms

8. Transport of drugs across membranes

9. Absorption of dmgs, orał bioavailability and presystemic elimination

10. Plasma protein binding and tissue distribution of drugs

11. Biotransfonnation of drugs

12. Excretion of drugs

13. Pharmacokinetics: zero and first order elimination. volume of distribution. clcarance. elimination half-life, orał bioavailability. calculation of loading and maintenance doses

14. Cholinergic agonists and cholinesterase inliibitors

15. Muscarinic receptor antagonists

16. Neuromuscular blocking agents. Drugs acting on autonomie ganglia