labie 3 RT-Associated Skeletal Injury in Children and Adults
Aspects of RT-Associated Skeletal Injury |
Children |
Adults |
General concem during RT planning |
High |
Low |
Primary issue |
Growth |
Necrosis. fracture |
Dose limit |
Low - 30 Gy |
High 60 Gy + |
Bonę at risk |
Any |
Mandible. weight bearing (ie femur) |
Common clinical scenarios |
Craniospinal irradiation. RT for sarcomas |
Head & neck cancer. prostatę cancer |