O volvulus LifeCycle

Onchocerca volvulus

Blackfly Stages

ABIackfly (genus Simultum) ^v takes a blood meal

Q L3 larvae

O Migrate to head

and blackftys probosos

(L3 latyae eoter bite woond)

Q Microfilariae pentrate ^ blackft/s midgut and migrate to thoracic muscles

A= lnfective Stage A= Diagnostic Stage

Humań Stages

O

Subcutaneous tissues

Adults produce unsheathed micfofilariae that typically are found in skin and in lymphatics of connective tissues. but also occasionally in peripheral blood. urine, and sputum.