OUTSIDE OF CELL
2 K+ expelled to inside; pump returns to initial State
Q 3 Na' are taken from inside
ADP
Q ATP
phosphorylates a subunit, stimulating conformational
change
INSIDE OF CELL
Two K* accepted from outside
Na* expelled into surroundings
Pump open to outside, ready to start second half of cycle
From Mathews and van Holde: Biochemlstry 2/e. © The Benjamin/Cummings Publishing Co., Inc.