Contents 2(3)

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Contents

Part II. Bacterial, Parasitic, and Viral Infections of the Liver

12    Innate and Adaptive Immune Responses to Bacterial and Parasite Infections:

Clinicopathological Conseąuences......................................................................................................... 153

Yalentina Medici, Lorenzo Rossaro, Sripriya Balasubramanian, and Stuart H. Cohen

13    Immune Response to Hepatitis A and E Viruses: Role in Disease Pathogenesis and Viral Elimination......... 163

Johannes Hadern and Michael P. Manns

14    Role of the Immune Response in Hepatitis B: Detenninants ofSeverity, Chronieity, and Response

to Antmral The rapy................................................................................................................................. 179

Antonio Bertoletti, Patrick Kennedy, and Adam J. Gehring

15 Immune Responses in Acute and Chronić Hepatitis C: Implications for Prognosis and The rapy............ 193

Heiner Wedemeyer, Markus Cornherg, and Michael P. Manns

16    Immunopathogenesis of Extrahepatic Manifestations in HAV. HBV, and HCV Infections:

Importance of Recognition and The rapy.................................................................................................209

Sven Piscltke, Arndt Yogel, Elmar Jaeckel, and Michael P. Manns

Part III. Autoimmune Liver Diseases

17    Immunogenetics of Autoimmune Liver Disease: Risk Factors for Susceptihility and Progression.........221

Peter Tickell Donaldson

18    Primary Biliary Cirrhosis and Autoimmune Cholangitis............................................................................235

Carlo Se Im i, Ana Lleo_y Piętro Invernizzi, and M. Erie Gershwin

19    Sclerosing Cholangitis: Primary and Secondary........................................................................................249

Sue Cullen and Roger Chapman

20    Autoimmune Hepatitis.................................................................................................................................263

Diego Yergani and Giorgina Mieli- Y erga ni

21    Unique Aspects of Autoimmune Hepatitis in Children..............................................................................277

Giorgina Mieli-Yergani and Diego Yergani

22    Overlap Syndromes of Autoimmune Hepatitis With Primary Biliary Cirrhosis and Primary

Sclerosing Cholangitis.............................................................................................................................285

Ulrich Beuers and Christian Rust

23    Animal Models of Autoimmune Liver Diseases.........................................................................................293

Markus Biburger and Gisa Tiegs

Part IV. Alcoholic and Nonalcoholic Fatty Liver Diseases

24    The Immune Response in the Pathogenesis of Alcoholic    Liver Disease...................................................309

Lynell W. Klassen and Geoffrey M. Thiele