F00574 017 f003
IN
Urea
OUT
IN
Creatinine
OUT
Reduced excretion
•RENAL FAILURE • Competition for tubular secretion (e.g. trimethoprim, cimetidine)
120 pmol/l Normal rangę
Reduced excretion
Hypovolaemia
High production
Rhabdomyolysis
n
|
{increased tubular resorption) •RENAL FAILURE |
• Large muscle mass | ||
|
6.6 mmol/l | |||
|
Normal rangę | |||
|
2.5 mmol/l Increased excretion • High urine flow (reduced tubular resorption) |
Low production • Smali muscle mass |
60 j.imol/1
High intake
• Gastrointestinal haemorrhage
• High-protein diet
High production
• Trauma, burns
• Serious infection
Low intake
• Anorexia, malnutrition
Low production
• Liver failure
© Elsevier. Boon et al.: Davidson's Principles and Practice of Medicine 20e - www.studentconsult.com
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