F00574 024 f006

Neutrophil	Causes of neutrophilia		Causes of neutropenia
	Infection	Malignancy	Infection
	Bacterial	Solid tumours	Viral
	Fungal	Hodgkin lymphoma	Bacterial. e.g. Salmonella
	Trauma	Myeloproliferative disease	Protozoal. e.g. malaria
GL#	Surgery	Polycythaemia	Drugs
	Burns Infarction Myocardial infarct	Chronić myeloid leukaemia Physiological Exercise	Box 24.10, p. 1014 Autoimmune Connective tissue disease
	Pulmonary embolus Sickle-cell crisis Inflammation Gout Rheumatoid arthritis Ulcerative colitis Crohn's disease	Pregnancy	Alcohol Bonę marrow infiltration Leukaemia Myleodysplasia Congenital Kostmann’s syndrome

Eosinophil

Basophil

Monocyte

%

Lymphocyte

Causes of basophilia

Myeloproiiferative disease Polycythaemia Chronić myeloid leukaemia Inflammation Acute hypersensitivity Ulcerative colitis Crohn's disease Iron deficiency

Causes of monocytosis

Infection

Bacterial, eg tuberculosis Inflammation

Connective tissue disease Ułcerative colitis Crohn‘s disease Malignancy Solid tumours

Causes of lymphocytosis

Infection

Viral

Bacterial, e.g. Bordetella pertussis Lymphoproliferative disease Chronić lymphatic leukaemia Lymphoma Post-splenectomy

Causes of lymphopenia

Inflammation

Connective tissue disease Lymphoma Renal failure Sarcoidosis Drugs

Corticosteroids Cytotoxics Congenital Severe combined immunodeficiency

© Elsevier. Boon et al.: Davidson's Principles and Practice of Mediclne 20e - www.studentconsult.com

%

Causes of eosinophilia

Allergy Hay fever Asthma Eczema

Infection

Parasitic

Drug hypersensitivity e.g. Gold. sulphonamides

Skin disease

Connective tissue disease Polyarteritis nodosa Malignancy Solid tumours Lymphomas