Neutrophils mobilised from bonę marrow in response to inflammation
Endothelial activation markers increased in response to inflammation. Neutrophils adhere to blood vessels and migrate into tissues
Engulfment of microorganisms followed by oxidative and non-oxidative killing
Failure to express leucocyte adhesion marfcers gives rise to Leucocyte adhesion deficiencies
___J
Failure of oxidative killing causes chronic granulomatous disease. Cytokine and cytokine receptor deficiencies result in susceptibility to mycobacterial infection
Neutrophil celi death and the formation of pus
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