F00574 004 f007
Failure of production of IgG antibodies: Common variable immune deficiency Specific antibody deficiency
Failure of B-cell maturation: X-linked agammaglobulinaemia
Immature B cells
Lymphoid
progenitors
Stern cells
Failure of T-cell co-stimulation: Hyper-IgM syndromey
IgM-producing B cells
r
Plasma cells
u ^
<
r
j-
Failure of lymphocyte precursors: Severe combined immune deficiency
c
Failure of IgA production: Selective IgA deficiency
Bonę marrow
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