inprinting u myszy
Genomie Imprinting iri the Mouse
(Reik et al.,Naturę 1987, 328: )
Hipoteza:
Imprinting polega na różnym stopniu metylacji genów w k.jajowych i plemnikach
Wprowadzony obcy gen służył do analizy metylacj
f| -'v.
jako marker. _
enzym
Hpa II
CcjGG
— = metylacja genu
— = brak metylacji
transgeniczny samiec 5 transgeniczna samica
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