ADCC przez komórki NK z udziałem przeciwciał
Antibody binds antigens on the surlace of target cells |
Fc receptora on NK cells recognize bound antibody |
Cross-linking of Fc receptors signals the NK celi to klll the target celi |
Target celi dles by apoptosis |
* A ** . A |
FcyRIII , (CD16) \ 11 / _j [ NK ccii ] A o ° o r o A. A A |
/ ( activated \ \ ( ^NKceiy \ killing /Wl° |
> |
Target celi |
Figurę 9-34 Immunobiology, 6/e. (C Garland Science 200S)