Tabela 4

labie 3. Primary and Secondary Outcomes.^1 ^2 3 4
Outcome	PCI Group (N = 1082}		Medical Therapy Group (N = 1084)		P Value	Hazard Ratio (95% Cl)
	No. of Outcomes	Estimated 4-Yr Cumuiative Event Ratę (%)	No. of Outcomes	Estimated 4-Yr Cumulative Event Ratę (%)
Centraily adjudicated
Primary end point	161	17.2	140	15.6	0.20	1.16 (0.92-1.45)
Death from all causes	87	9.1	84	9.4	0.83	1.03 (0.77-1.40)
Fatal and nonfatal reinfarctionf	59	7.0	44	5.3	0.13	1.36 (0.92-2.00)
Procedure-related	6		1
Not temporally related to procedurę	53		43
Nonfatal reinfarction	57	6.9	40	5.0	0.08	1.44 (0.96-2.16)
NYHA class IV heart failure:!:	43	4.4	44	4.5	0.92	0.98 (0.64-1.49)
Cardiovascular death	58	6.3	52	5.0	0.56	1.12 (0.77-1.63)
Death or nonfatal reinfarction	139	14.9	116	13.2	0.13	1.21 (0.95-1.55)
NYHA class III or IV heart failure:j:	57	5.9	61	6.2	0.72	0.94 (0.65-1.34)
Death, reinfarction, or NYHA class III or IV heart failureY	173	18.2	153	16.9	0.24	1.14 (0.92-1.42)
Stroke	16	1.7	19	2.0	0.62	0.84 (0.43-1.64)
Site-determined
Primary end point	170	18.2	142	16.2	0.09	1.22 (0.97-1.52)
Fatal and nonfatal reinfarction	89	10.1	66	8.1	0.05	1.37 (1.00-1.89)
Procedure-related	17		7
Not temporally related to procedurę	72		59
Nonfatal reinfarction	80	9.4	57	7.2	0.04	1.43 (1.02-2.00)
NYHA class 111—1V heart failure	61	6.2	67	7.0	0.61	0.91 (0.65-1.29)
Hospitalization or treatment for any class of heart failure	75	7.4	77	8.1	0.89	0.98 (0.71-1.34)
Revascularization (PCI orCABG) ex-cluding protocol-assigned PCI§	170	18.4	205	22.0	0.03	0.81 (0.66-0.99)
CABG	38	4.3	40	4.8	0.81	0.95 (0.61-1.48)
Repeated elevation of cardiac marker
Within 48 hr after randomization — no./total no. (%)	101/1012 (10.0)		30/918 (3.3)		<o.ooin

1

P values were calculated with the use of the log-rank test for Kaplan-Meier curves through 5 years of follow-up, unless otherwise noted.

2

f Two of 44 patients in the medical therapy group did not have elevated serum cardiac markers but had pain and changes on electrocardiography.

3

t Ali patients reaching the end point of heart failure required hospitalization or admission to a short-stay unit. Data on the site-reported func-tional class of heart failure are available in the Supplementary Appendix.

4

In 58 patients in the PCI group, the procedurę was repeated in the infarct-related artery, in 14 of the patients at 1 week or less after the oc-currence of an adjudicated reinfarction. In 106 patients assigned to medical therapy, PCI of the infarct-related artery was performed, in 6 of the patients at 1 week or less after the occurrence of an adjudicated reinfarction.

*|The P value was calculated with the use of the chi-square test.