Risk for double segment imbalance:
trisomy 4pl5.2-*pter and monosomy 9pl3—>pter or ni on os o my 4pl52-»pter and trisomy 9pl3-»pter
aftcr 2 : 2 disjimction and adjacent - 1 segregation
segment: 4pl5.2—>pter: segment: 9pl3-*pter
risk: 29% ± 8% (8/27) risk: 6,4% ± 3% (3/47)
6,4% : 2 - 3.2%
Overal risk at birth: MAT/PAT: 3,2% Co nipa rabie with direct analysis: 33%