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Pancreas Structuri-

GASTROINTESTINAL PHYSIOLOGY

V    / Root of

Superior mesenteric vessels mesentery

Low-power section of pancreas 1. Acini, 2. islet, 3. interlobular septum, 4. interlobular duet

High magnification: acini, intercalated duet and zymogen granules

Common bile duci Principal pancreatic ducl (Wirsung's)

Accessory pancreatic duet (Santorini's)

Pancreatic islet: A (=«-).

B i = |J—), and D 1=6-) cells. 1. Reticulum, 2. acini

Figurę 7.26 Pancreas Structure_

The pancreas has exocrine and endocrine components. The acinar cells of the exocrine pancreas secrete a number of enzymes that are necessary for digestion of protein, starches, and fats. The ductal cells secrete fluid, with a high HCO/ content. This HCOr serves to neu-tralize the acid entering the duodenum from the stornach. The endocrine pancreas consists of the islets of Langerhans. Within the islets, the A- or a-cells (located in the periphery of the isletj secrete glucagon, the B- or /3<ells (located centrally in the islet) secrete insulin, and the D- or &cells (dispersed throughout the islet) secrete somatostatin.

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