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Figurę 7: Expression of MHC-I on B16gp33 cells following VSV infection. (a) B16gp33 cells were infected at an MOI of 10 or mock-infected. At 24 hours post-infection, cells were labeled to measure MHC-I expression by flow cytometry. Data are the mean ± SEM and representative of two independent experiments in triplicates. (b) B16gp33-bearing mice (n= 4-5) were also infected locally at the tumor site with 5.0 x 108 PFU of WT or mutant VSV on day 7. The following day, tumors were isolated and (b) labeled for the detection of MHC-I expression on CD45' cells or (c) cocultured with CFSE-labeled P14 transgenic splenocytes to analyze degranulation efficacy of CD8+CFSE+ cells *P < 0.05, **P < 0.01, ***P < 0.001.
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