4613347756

4613347756



Figurę 5: Adoptive transfer of activated D8 T lymphocytes limits tumor progress'on.

B16gp33-beanng mice (n=10) were infected locally at the tumor site with 5 0 x 108 PFU of WT, mutant VSV or mock infected on day 7, 9 and 11 On day 8 following the first VSV dose, the spleen was harvested and CD8+ T cel s punfied. 5 0 x 106 cells were transferred intravenously mto naive recipients 24 hours pnor to parental B16 moculation and tumor growth was measured (a). Data represents the mean ± SEM and is representative of two independent expenments Overall survival (n=20) was also assessed (b) and data are from two independent expenments combined. *P 0 05, **P 0.01

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