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tumor-specific CD8 T lymphocytes. Inhibition of complement proteins also acts on MDSC and limits the immunosuppressive tumor microenvironment leading to increased CTL activation. Abbreviations: CTL, cytotoxic T lymphocyte; CVF, cobra venom factor; IFNy, interferon gamma; iDC, immature dendritic celi; mDC, maturę dendritic celi; MDSC, myeloid-derived suppressor celi; NK, natural killer celi; TNFa, tumor-necrosis factor alpha.
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