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Director’s Situation Update
Monday
11 May 2009 1100 EDT
Day 23
Day of Vaccine Planning
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Novel Influenza A (H1N1) Key Events
11 May 2009
•
Novel Influenza A (H1N1) Declarations
–
WHO: Pandemic Phase 5 (29 Apr 1600 EDT)
–
Declarations of Emergency (no changes)
•
USG: Public Health Emergency declared (26 Apr 2009)
•
SLTT Declarations: 10
– CA, TX, WI, FL, NE, VA, MD, IA, OH, American Samoa
•
National Declarations: 4
– Ecuador, Costa Rica, Colombia, Mexico
•
US Cases:
–
Confirmed: 2,618 cases (
ç
86)
•
2,614 cases, 43 States; 4 cases DC
–
Probable: 704 cases
•
698 cases, 40 States; 6 cases DC
–
Confirmed/Probable: 3,322 cases (
è
75)
•
3,312 cases, 46 States; 10 cases DC
–
Third fatality in US identified in WA
•
Total Deaths 3: (2-TX, 1-WA )
•
International Cases: 4,694 in 30 Countries
–
New countries with confirmed cases: Norway, China
•
Deployments: 116 deployed, 34 pending
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Novel Influenza A (H1N1)
11 May 2009
Strategic Objectives / Principles
1. Reduce illness and death
2. Minimize societal impact
3. Put greatest effort in activities with greatest
impact
Zones of Effort
1. Understanding the problem
2. Public Health Interventions
3. Communications
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Epidemiology/Surveillance Team
Novel Influenza A (H1N1) Cases as of 11 May 2009 1100 EDT
# State
Cases
#
States
# DC
Cases
TTL
States+DC
# State
Cases
#
States
# DC
Cases
TTL
States+DC
# State
Cases
#
States
11-May
2,614
43
4
2,618
93
21
1
94
3
2
Change
(5/10 to 5/11)
86
0
0
86
(-4)
0
0
(-4)
0
0
# State
Cases
#
States
# DC
Cases
TTL
States+DC
# State
Cases
#
States
# DC
Cases
TTL
States+DC
# State
Cases
#
States
11-May
3,312
46
10
3,322
109
24
1
110
3
2
Change
(5/10 to 5/11)
(-75)
0
0
(-75)
(-10)
0
0
(-10)
0
0
Confirmed (CDC Lab)
Total Confirmed and Probable
Cases
Hosp Deaths
Cases
Hosp Deaths
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0
20
40
60
80
100
120
140
160
180
200
220
28-
M
ar
30
-Ma
r
1-Ap
r
3-A
pr
5-
A
pr
7-
A
pr
9-A
pr
11
-A
pr
13
-A
pr
15
-Ap
r
17
-A
pr
19
-A
pr
21
-Ap
r
23
-Ap
r
25
-A
pr
27
-Ap
r
29
-Ap
r
1-
M
ay
3-M
ay
5-
M
ay
7-
M
ay
9-
M
ay
D
Date of Illness onset
lness Onset
N
o
. o
f C
a
s
e
s
Confirmed
Probable
Underreporting over weekend:
No. states reporting:
May 9, n=24
May 10, n=21
Epidemiology/Surveillance Team
Cases by Date of Onset as of 11 May 2009 1100 EDT
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Epidemiology/Surveillance Team
Age Group by Case Status as of 11 May 2009 1100 EDT
0
100
200
300
400
500
600
700
0-4 years
5-17 years 18-49 years 50-64 years >=65 years
Age
Nu
m
b
e
r o
f Ca
s
e
s
Confirmed
Confirmed and Probable
*Age available for 962/2618 confirmed and 244/704 probable cases.
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Epidemiology/Surveillance Team
Confirmed Cases Descriptive Statistics as of 11 May 2009 1100 EDT
– Median age: 15 years, range 1 month- 86 years
– 62% (633/1026): age <18 years
– 16 cases: age <12 months
– Gender: 49% female
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NOTE: Week ending dates vary by influenza season
*Preliminary ILI data for week 17, as of May 10, 2009 (n=1,081 weekly ILI reports received from 50 states)
† There was no week 53 during the 2006-07 and 2007-08 seasons, therefore the week 53 data point for those seasons is an average of weeks 52 and 1.
% ILI Visits Reported by US Outpatient Influenza-like Illness Surveillance Network (ILINet),
National Summary 2008-09 and Previous Two Seasons
(No updates since last report)
0
1
2
3
4
5
6
7
10
/4
10
/1
8
11
/1
11
/1
5
11
/2
9
12
/1
3
12
/2
7
1/
10
1/
24
2/
7
2/
21
3/
7
3/
21
4/
4
4/
18
5/
2
5/
16
Week Ending Dates
%
o
f V
is
its
fo
r
IL
I
2006-07†
2007-08†
2008-09
National Baseline
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Epidemiology/Surveillance
Assessment & Planning 11 May 2009
• Assessment:
– Current case counts represent low case reporting
by states May 9-10
– Expect significant increase in numbers reported
May 11
• Plan:
– Continuing to review general epi trends as well as
info from HCP and pregnancy activities
– Anticipating additional data from field studies
over next several days, including household
attack rates, estimates of duration of symptoms
from shedding study
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International
Novel Influenza A (H1N1) - 11 May 2009
•
WHO global case count: 4,694 confirmed cases in 30 countries*
– No major increase in cases since yesterday’s report
– New countries with confirmed cases:
Norway, China
**
– China’s first confirmed case:
• 30 y.o. male studying at unspecified US university
• Departure flight from US was out of St. Louis
– Countries with highest confirmed case count after the US and
Mexico:
• Canada: 284 (
ç
4) Spain: 95 (=) UK: 47 (
ç
4)
•
Two documents being finalized
– Research Agenda for Tropics and Southern Hemisphere
– CDC Strategy for H1N1 Pandemic Mitigation in the Imminent
Southern Influenza Season
•
*Note: WHO case counts are current as of 05/11/09, 6:00 am EDT
•
**First case in mainland China. 1 case previously confirmed in
Hong Kong.
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Division of Global Migration and Quarantine
Novel Influenza A (H1N1) - 11 May 2009
•
Ports of Entry (POEs)
– 157 response events, 15 confirmed after referral at POE
(10 May)
– Hawaii DOH conducting enhanced sentinel
surveillance:
• Swabs for arriving domestic and international travelers
with ILI symptoms
– Positive travelers encouraged to self-isolate
•
Community Mitigation (CM)
– Epi-Aids: NPI - NY, Chicago, Delaware
– Ft Worth School closure evaluation under review
– Community Mitigation Team arrived Mexico City, 9 May
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Vaccine
Novel Influenza A (H1N1) - 11 May 2009
• Activities
– Developing recommendations around use of
remaining 2008-09 Northern Hemisphere seasonal
vaccine (week of 5/11/09)
• Plans Unit mission analysis
• Strategy meeting on unintended consequences
• ACIP influenza work group call
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Animal/Human
Novel Influenza A (H1N1) - 11 May 2009
• High Pathogenic Avian Influenza (HPAI)
– H5N1 OIE confirmed outbreaks in past 3
weeks
*WHO, May 6, 2009: 423 cases total, 258 fatal (61.19%)
Human Cases of Avian Influenza
Human Cases of Avian Influenza
H5N1 2003
H5N1 2003
-
-
2009*
2009*
4
32
43
79
59
33
8
0
14
55
36
29
11
20
0
20
40
60
80
100
120
2003
2004
2005
2006
2007
2008
2009
Fatal
Non-Fatal
88
115
98
46
4
44
28
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Communications Summary
Novel Influenza A (H1N1) - 11 May 2009
Domestic Communication
Channel Traffic
Web Page Views: 729, 366 (-49%)
Public Inquires: 290 (-55%)
Print/Internet News Stories: 241 (-3%)
National Television Stories: 26 (+63%)
Local Television Stories: 320 (-20%)
Themes
Print/Internet—Focus on International
Themes
New flu kills US man, spreads to
Australia, Japan
Emerging themes (all news channels)
•
Criticism of warning system – WHO
needs mechanism to dial down the
anxiety levels while educating about the
extent of transmission.
Spanish Language Media Monitoring
(global outlets; machine translation)
Coverage, generally non-sensational,
factual, and non-critical
•
Case count continues to mount
rapidly
•
Secondary transmission instances
noted in Europe
•
Illness course mild-moderate and
self-limiting
•
Fatal cases (Costa Rica, Canada) in
presence of underlying (chronic)
disease or disorder
•
Economic losses in Mexico,
substantial though effort underway
to “normalize” activities
Public Inquiries: CDC-INFO emails/calls
•
Symptoms? 23%
•
Incubation Period?
12%
•
Travel recommendations?
10%