ABCOR® PHARMACEUTICAL GRADE SPIRAL ELEMENTS
HFK-131 and HFK-328 Spiral Wound Ultrafiltration Modules
Membrane Chemistry: Proprietary semi-permeable polyethersulfone (PES)
PRODUCT
Membrane Type: HFK-131 with observed separation range of 10,000 Daltons
DESCRIPTION
HFK-328 with observed separation range of 5,000 Daltons
Construction: Spiral wound element with sanitary tailed or net wrap outer layer
Applications: For enzyme purification, protein concentration, and protein fractionation.
Specifically designed to conform to FDA guidelines.
Options: Feed channel spacers; NYV/T (31 mil),VYV/T (46 mil), HYV/T (62 mil),
FYV/T (80 mil). Modules lengths; 33 , 35.5 and 38
Model Nominal Active Membrane Area
SPECIFICATIONS
NYV/T Spacer (31 mil) VYV/T Spacer (46 mil) HYV/T Spacer (62 mil) FYV/T Spacer (80 mil)
ft2 (m2) ft2 (m2) ft2 (m2) ft2 (m2)
ABCOR® 3838 HFK-131/328 64 (5.9) 53 (4.9) 43 (4.0) 35 (3.2)
ABCOR® 4333 HFK-131/328 85 (7.9) 69 (6.4) 51 (4.7) 43 (4.0)
ABCOR® 4336 HFK-131/328 86 (8.0) 74 (6.9) 56 (5.2) 47 (4.4)
ABCOR® 4338 HFK-131/328 93 (8.6) 76 (7.1) 60 (5.6) 50 (4.6)
ABCOR® 6338 HFK-131/328 213 (19.8) 171 (15.9) 132 (12.2) 108 (10.0)
ABCOR® 8338 HFK-131/328 342 (31.8) 284 (26.4) 224 (20.8) 169 (15.7)
Typical operating pressure: 30 - 120 psi (2.1 - 8.3 bar)
RECOMMENDED
Operating temperature range: 40 - 130°F (5 - 55°C)
OPERATING
Cleaning temperature range: 105 - 122°F (40 - 50°C)
LIMITS
Allowable pH - continuous operation: 2.0 - 10.0
Allowable pH - Clean-In-Place (CIP): 1.8 - 11.0
Design pressure drop per element: N or V spacer: 12-20 psi (0.8-1.4 bar)
H or F spacer: 15-25 psi (1.0-1.7 bar)
Design pressure drop per vessel (3 in series): N or V spacer: 36-60 psi (2.5-4.1 bar)
H or F spacer: 45-75 psi (3.1-5.2 bar)
Design pressure drop per vessel (4 in series): N or V spacer: 48-68 psi (3.3-4.7 bar)
H or F spacer: 60-90 psi (4.1-6.2 bar)
PRODUCT
DIMENSIONS
Model A B C
inches (mm) inches (mm) inches (mm)
ABCOR® 3838 HFK-131/328 38.0 (965) 3.8 (96.0) 0.831 (21.1)
ABCOR® 4333 HFK-131/328 33.0 (838) 4.3 (109.0) 0.831 (21.1)
ABCOR® 4336 HFK-131/328 35.5 (902) 4.3 (109.0) 0.831 (21.1)
ABCOR® 4338 HFK-131/328 38.0 (965) 4.3 (109.0) 0.831 (21.1)
ABCOR® 6338 HFK-131/328 38.0 (965) 6.3 (160.0) 1.138 (28.9)
ABCOR® 8338 HFK-131/328 38.0 (965) 8.3 (211.0) 1.138 (28.9)
ABCOR® PHARMACEUTICAL GRADE SPIRAL ELEMENTS
Membrane Characteristics: Sanitizing should be done only after a complete
The membrane used in these modules consists of a cleaning cycle and with water of acceptable quality -
semipermeable polyethersulfone (PES) layer on a refer to cleaning instructions and feedwater quality
polyester backing material. technical bulletins.
Pure water flux of these PES HFK membranes are 1.0-
2.2 gfd/psi (24-53 l/m2/h/bar) at 77°F (25°C). Cationic (Positively Charged) Polymers and
Surfactants:
Operating Limits: PES membranes may be irreversibly fouled if exposed to
Operating Pressure: Maximum operating pressure is cationic (positively charged) polymers or surfactants.
140 psi (9.7 bar). Exposure to these chemicals during operation or cleaning is
Permeate Pressure: Permeate pressure should not not recommended and will void the warranty.
exceed baseline (concentrate) pressure at any time
(including online, off-line and during transition). Reverse Lubricants:
pressure will damage the membrane. For module installation, use only water or glycerin to
Differential Pressure: The maximum differential lubricate seals. The use of petroleum or vegetable-based
pressure per module is listed in the front of this oils or solvents may damage the module and will void the
document, including design values for multi-element warranty
housings.
Temperature: Maximum operating temperature is Supplemental Technical Bulletins:
130°F(55°C), maximum cleaning temperature is UF Module Cleaning Procedures
122°F(50°C). Water Quality Guidelines for CIP and Diafiltration
pH: Allowable range for continuous operation is 2.0 to
10.0. Service and Ongoing Technical Support:
Koch Membrane Systems (KMS) has an experienced staff
Water Quality for Cleaning & Diafiltration: of professionals available to assist end-users and OEMs for
pH: Allowable range for cleaning is 1.8 to 11.0. optimization of existing systems and support with the
Turbidity and SDI: Maximum feed turbidity is 1 NTU. development of new applications. Along with the availability
Maximum feed SDI is 5.0 (15-minute test). of supplemental technical bulletins, KMS also offers a
Guidelines: Please refer to the KMS  Water Quality complete line of KOCHTREAT® and KOCHKLEEN®
Guidelines for CIP and Diafiltration for more detailed membrane pretreatment, cleaning and maintenance
information. chemicals.
Chlorine and Chemical Exposure: KMS' Capability
Cleaning and sanitizing limits for chemical KMS is the leader in crossflow membrane technology,
concentrations, pH, temperature and exposure time must manufacturing reverse osmosis, nanofiltration, microfiltra-
be observed in order to achieve maximum useful module tion, and ultrafiltration membranes and membrane systems.
life and to maintain the warranty. The industries we serve include food, dairy and beverage,
Iron or other catalyzing metals in the presence of free semiconductors, automotive, water and wastewater,
chlorine or hydrogen peroxide will accelerate membrane chemical and general manufacturing. KMS adds value by
degradation. providing top quality membrane products and by sharing our
experience in the design and supply of thousands of
crossflow membrane systems worldwide.
The information contained in this publication is believed to be accurate and reliable, but is not to be construed as implying any warranty or guarantee of performance. We assume no responsibility,
obligation or liability for results obtained or damages incurred through the application of the information contained herein. Refer to Standard Terms and Conditions of Sale and Performance Warranty
documentation for additional information.
Koch Membrane Systems, Inc., www.kochmembrane.com
Corporate Headquarters: 850 Main Street, Wilmington, Massachusetts 01887-3388, USA, Tel. Toll Free: 1-888-677-5624, Telephone: [phone], Fax: [phone]
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ABCOR®, KOCHKLEEN®, KOCHTREAT® are registered trademarks of Koch Membrane Systems, Inc.
Koch Membrane Systems, Inc. is a Koch Chemical Technology Group, LLC company.
© 2006 Koch Membrane Systems, Inc. All rights reserved worldwide. 9/06