100669
If the percentage of free drug in the plasma divided by the apparent volume of distribution, Vd (per kilogram of body weight), is greater than 80, 6 hours of hemodialysis should remove a significant amount (20-50%) of a drug.
If the percentage of free drug divided by the apparent volume of distribution (per kilogram of body weight) is less than 20, then a smali and probably insignificant amount (<10%) of the drug will be removed d u ring 6
hours of hemodialysis.
|
% Free dru g . Vo(L/kg) |
20-50% removed by hemodialysis |
|
% Free dru g ^ Vn(L/kg) |
< 10% removed by hemodialysis |
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