The macrophage expresses recoptors for many bacterial constituents
mannose
receptor
LPS receptor (CD14)
TLR-4
Bnctcria blnding to macrophage recoptors initiatc the rolease of cytokinos and smali lipid mediators of inflammation
lipid mediators
► LPS
cytokines ^<7 ®
O
chemokines
Macrophages ongulf and dłgest bacteria to which thoy bind
phagosome
lysosome
phagolysosome
Figurę 2-5 Immunobiology, 6/e. (C Garland Science 200S)