Stagc |
Steps in rcplication |
Drug targcts |
1 |
Attachment to CD4 receptor | |
2 |
Binding to co-receptor CCR5 or CXCR4 |
CCR5/CXCR4 receptor inhibitors |
3 |
Fusion |
Fusion inhibitors |
4 |
Reverse transcription |
Nucleoside and non-nucleoside reverse transcription inhibitors |
5 |
Integration |
Integrase inhibitors |
6 |
Transcription | |
7 |
Translation | |
8 |
Cleavage of polypeptides and assembly |
Protease inhibitors |
9 |
Viral release |
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