3

Mlc

Aciivc

repressor

FIGURĘ 9.18 Sequestration of Mlc by PtsG Protein

A)    The membranę transporter PtsG has an open channel for glucose when it is phosphorylated (P).

B)    Glucose enters the celi and is converted into glucose-6-phosphate so removing the phosphate.

C)    Tbe dephosphorylated PtsG protein binds the Mlc repressor. This inactivates the Mlc repressor as

it can no longer bind DNA when trapped by PtsG. If the supply of glucose runs out, PtsG will be able to retain its phosphate and Mlc is released.

Glucose (goes lllt Oliwii channel)

Glucose-4>-P

(yropiASM

Cell