IMGP5911 (2)

olecular genetłc tcsting:

illgcnc scqucncing. Mulalion dctcction ratę i* up to 90 /•.

ulation scanning. A variety «f mulalion scanning methods e used. Mulalion detection rale ii approsimately 80-90%.

T aionc. Most mulalion* in thc A PC gcne causc prcmaturi Hicationof thc A PC protein. A test bascd on Ihi* i* posilili? out 80% of individuals wigh FAP.

ulhern biot analysis. This method idcntific* « plications invoiving one or morę exons of AP rceniagc of indń iduais with FAP wiio havc a irrangemcnl involving duplication or dclction