IMG 69 (4)

Cryptopatches /CPsf

CPs are loosely organized cinsters of appimmateły 1000 cdklocateddtkebaseofthe intestinal epithelial rrypts CPs are comprised primarih of thret cdi types: lineage marker negative (Iin-)r-kit⁺ celis, dcndritk refls (DCs), md vasci]ar ceB adhesion moknie (VCAM)-1⁺ stromal refls.

Functions:

1.    Several studies suggest that CPsaresitesforthe generation of intraepithelial T lymphocytes.

2.    The lirrc-kiP CP cells may be responsible for organizing lymphoid structures in the intestine, and CPs may be precursors to ILFs