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Strudure of łhe plasmamembranę ”

Tht plasrna membranę defines tbe border of a celi,and quoujs łbe celi to interaci u>itn its tr\v\YOY)mr\\

^ *toke in and excrete VGriou$ suk>stqnces •• lipids->semi-permeabie barrier ^ communication witn ottier celłs ⁰ lipicb- semi- permeabie barrier ⁰ proteiną: transport and communication o carbohqclrcvłe$: decorate proteiny and lipids, ceu reco^nition

currentitj acccp+ecl piasmci membranę °p.m. i'sa mosaic of components -tncu move freelq and fiuidit\ -> dqnam»c    Qiqc.oprotein

proces s    pnospnoiipid

Components-    biiaijer

° pnospnolipids (p.i. bilaqer)l (MO⁰^ I o cboiesterol    ]    \

o membranę proteins (50%') o attacneci carbohqclrate Qroups (1070)

>-> ą\iĄCopr<ńt\nsl Qlqcolipids

model

Cjlq co lipid

ptT\pY)ZrQ\

memprane

integrai    cqloskeietal    protein

memprane    fiiaments    cbanne)

protelns

Make up the basie fabric of the p.m.. arranged ina bilaqer o amphipathic 1 hqdropbiiic nedd and hqdropftODlc tails

^ head (phosphate ęjroupt ęiyceroi) oato)drd-> contacting a^ueous fluid inside/outside celi

tails (fcittcj acids) inuiards-» react a)ifh each other and forma oiiaqer ⁰ uoater/polar sub-s+emces cannot cross easiiM

Phospbolipids spontaneous«q (under ri^nt conditions') arran^e into micelies / liposomes amen in an ac^ueous soiution -*ceii ancestor?

Integra! membranę proteins: integrated inio the membranę

^ hqdrophobic region connected to biiager core Trcmsmembrane pro-łzW^s - zy.tzr\ó acrosS the membranę (mtegral)

^can cross łbe membranę 1-lZtimes ^some have channeis łlnat cillow possane

Peripneral membranę protems: found on the outside/inside surfaces of membranes. ⁰ QiiQCY\ea io Integra! p^o\t\i\s/ pnospnolipicu o looselq ałfacheó, clo no-\ stick into the core

liposome mice l|e (cross - sections')

found On tne outside surface on proieins/Iipids ⁰ 2‘6o wonosoccharide. units-* straight or branened

•^arkers

• differentiafe between oodq celis and fore»gn celis