Editorial

Please find listed below ‘‘The Ten Most Highly

Cited Articles’’ and ‘‘The Ten Most Frequently
Downloaded Articles’’ in the

Journal of Pharma-

ceutical Sciences (JPharmSci

TM

) in 2008. Note

that in tabulating these lists we considered all
papers published in

JPharmSci

TM

irrespective of

their date of publication. The journal’s Editorial
Team feels that this information will be of
great interest to the authors who publish their
manuscripts in

JPharmSci

TM

since it reflects in

‘‘citation metrics’’ and ‘‘usage metrics’’ the pre-
vailing interests of the journal’s readers.

I am very pleased to report that the impact of

JPharmSci

TM

, as judged by ‘‘citation metrics,’’

increased significantly in 2007 (impact factor

¼

2.94) as compared to 2006 (impact factor

¼ 2.23). It

is equally important to mention that the journal’s
impact as judged by ‘‘usage metrics’’ (i.e., article
downloads) continues to grow significantly in
2008. For example, papers published in

JPharm

Sci

TM

from 1996 to 2008 were downloaded 337,090

times from the journal’s website in 2008. This
represents a 6.5% increase in the number of ‘‘full
text’’ downloads compared to 2007. In 2008 the
papers in the ‘‘Ten Most Frequently Downloaded
Articles’’ (see below) were downloaded from 952 to
1316 times. Finally, it is interesting to note that
papers published in

JPharmSci

TM

from 1912 to

1995 were downloaded 52,895 times from the
journal’s website in 2008. In my opinion, this
statistic reflects the ‘‘long term impact’’ that
research results published in

JPharmSci

TM

have

on the pharmaceutical sciences.

The Ten Most Frequently Downloaded Articles

in 2008

(1) Wei Wang, Satish Singh, David L. Zeng,

Kevin King, and Sandeep Nema, ‘‘Anti-
body Structure, Instability, and Formula-
tion’’,

J. Pharm. Sci., 96, 1–26, 2007

(Minireview).

(2) Ana Ruiz-Garcia, Marival Bermejo, Aaron

Moss, and Vicente G. Casabo, ‘‘Pharmaco-

kinetics in Drug Discovery’’,

J. Pharm.

Sci., 97, 654–690, 2008 (Review).

(3) Evelyn D. Lobo, Ryan J. Hansen, and

Joseph P. Balthasar, ‘‘Antibody Pharma-
cokinetics

and

Pharmacodynamics’’,

J. Pharm. Sci., 93, 2645–2668, 2004 (Mini-
review).

(4) Farahidah Mohamed and Christopher F.

van der Walle, ‘‘Engineering Biodegrad-
able Polyester Particles With Specific
Drug Targeting and Drug Release Proper-
ties’’,

J. Pharm. Sci., 97, 71–87, 2008

(Review).

(5) Abu T. M. Serajuddin, ‘‘Solid Dispersion of

Poorly Water-Soluble Drugs: Early Pro-
mises, Subsequent Problems, and Recent
Breakthroughs’’,

J. Pharm. Sci., 88, 1058–

1066, 1999 (Research Article).

(6) Yiyun Cheng, Zhenhua Xu, Minglu Ma,

and Tongwen Xu, ‘‘Dendrimers as Drug
Carriers: Applications in Different Routes
of Drug Administration’’,

J. Pharm. Sci.,

97, 123–143, 2008 (Review).

(7) Christina Foerg and Hans P. Merkle,

‘‘On the Biomedical Promise of Cell
Penetrating Peptides: Limits Versus Pro-
spects’’,

J. Pharm. Sci., 97, 144–162, 2008

(Review).

(8) Joshua S. Boateng, Kerr H. Matthews,

Howard N.E. Stevens, and Gillian M.
Eccleston, ‘‘Wound Healing Dressings
and Drug Delivery Systems: A Review’’,
J. Pharm. Sci., 97, 2892–2923, 2008
(Review).

(9) Harikrishna Devalapally, Ananthsrinivas

Chakilam, and Mansoor M. Amiji, ‘‘Role of
Nanotechnology in Pharmaceutical Pro-
duct Development’’,

J. Pharm. Sci., 96,

2547–2565, 2007 (Review).

(10) Jenny Y. Chien and Rodney J.Y. Ho, ‘‘Drug

Delivery Trends in Clinical Trials and
Translational Medicine’’,

J. Pharm. Sci.,

97, 2543–2547, 2008 (Commentary).

The Ten Most Highly Cited Articles in 2008

(1) Abu T. M. Serajuddin, ‘‘Solid Dispersion of

Poorly Water-Soluble Drugs: Early Pro-

Journal of Pharmaceutical Sciences, Vol. 98, 1603–1604 (2009)

ß 2009 Wiley-Liss, Inc. and the American Pharmacists Association

JOURNAL OF PHARMACEUTICAL SCIENCES, VOL. 98, NO. 5, MAY 2009

1603

mises, Subsequent Problems, and Recent
Breakthroughs’’,

J. Pharm. Sci., 88, 1058–

1066, 1999 (Research Article).

(2) Tianshun Lian and Rodney J. Y. Ho,

‘‘Trends and Developments in Liposome
Drug Delivery Systems’’,

J. Pharm. Sci.,

90, 667–680, 2001 (Minireview).

(3) Monica L. Adams, Afsaneh Lavasanifar,

and Glen S. Kwon, ‘‘Amphiphilic Block
Copolymers for Drug Delivery’’,

J. Pharm.

Sci., 92, 1343–1355, 2003 (Minireview).

(4) Jennifer D. Irvine, Lori Takahashi, Karen

Lockhart, Jonathan Cheong, John W.
Tolan, H. E. Selick, and J. Russell Grove,
‘‘MDCK (Madin-Darby Canine Kidney)
Cells: A Tool for Membrane Permeability
Screening’’,

J. Pharm. Sci., 88, 28–33,

1999 (Research Article).

(5) Sebastien Henry, Devin V. McAllister,

Mark G. Allen, and Mark R. Prausnitz,
‘‘Microfabricated Microneedles: A Novel
Approach to Transdermal Drug Delivery’’,
J. Pharm. Sci., 87, 922–925, 1998
(Research Article).

(6) Christopher M. Wiethoff and C. Russell

Middaugh, ‘‘Barriers to Nonviral Gene
Delivery’’,

J. Pharm. Sci., 92, 203–217,

2003 (Minireview).

(7) Barbara Stella, Silvia Arpicco, Maria Ter-

esa Peracchia, Didier Desmae¨le, Johan
Hoebeke, Michel Renoir, Jean D’Angelo,
Luigi

Cattel,

and

Patrick

Couvreur,

‘‘Design of Folic Acid-Conjugated Nano-
particles for Drug Targeting’’,

J. Pharm.

Sci., 89, 1452–1464, 2000 (Research
Article).

(8) Bruce J. Aungst, ‘‘Intestinal Permeation

Enhancers’’,

J. Pharm. Sci., 89, 429–442,

2000 (Minireview).

(9) David E. Clark, ‘‘Rapid Calculation of

Polar Molecular Surface Area and Its
Application to the Prediction of Transport
Phenomena. 1. Prediction of Intestinal
Absorption’’,

J. Pharm. Sci., 88, 807–814,

1999 (Research Article).

(10) Hans

Lennerna¨s,

‘‘Human

Intestinal

Permeability’’,

J. Pharm. Sci., 87, 403–

410, 1998 (Minireview).

In addition to the ‘‘citation and usage’’ informa-

tion provided above, please note that anyone
can view the ten most accessed (i.e., downloads)
papers published in

JPharmSci

TM

in the past

six months, as well as the ten most cited
papers in 2007–2008 by going to http://www3.in-
terscience.wiley.com/journal/68503813/home and
clicking on the ‘‘Most Accessed’’ or ‘‘Most Cited’’
links.

Finally, please be advised that Wiley Inter-

science has agreed to make ‘‘usage’’ information
available to authors of papers published in
JPharmSci

TM

. Authors can now request this

information

by

contacting

Tammy

Dunning

([e-mail]).

Ronald T. Borchardt, Editor

Journal of Pharmaceutical Sciences

Published online in 00 Month 2009

Wiley InterScience (www.interscience.wiley.com)

DOI 10.1002/jps.21755

JOURNAL OF PHARMACEUTICAL SCIENCES, VOL. 98, NO. 5, MAY 2009

DOI 10.1002/jps

1604

BORCHARDT